DNA repair
Cellular mechanism
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We include updates on BRCA1, Homologous recombination, Non-homologous end joining, Deinococcus radiodurans, Proliferating cell nuclear antigen, BRCA2, RecA, Photolyase, RecBCD, SOS response, RecQ helicase, LexA repressor, AP site, SOS box, Steven A. Leadon, Excinuclease ... and more.
| 2022 |
Deinococcus radiodurans
Horne et al. conducted a study on Deinococcus radiodurans examining its survivability under desiccation and freezing conditions, specifically exploring its potential relevance to microbial life on Mars. The research revealed that desiccated and frozen cells could resist up to 140 kGy of radiation, corresponding to a theoretical survival time of 280 million years at a depth of 33 feet below the Martian surface.
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| 2020 |
Homologous recombination
An outbreak on the Diamond Princess cruise ship was traced to a potential RNA recombination event, with the 11083G > T mutation spreading during shipboard quarantine under positive selection pressure.
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| 2020 |
Homologous recombination
During the COVID-19 pandemic, genomic sequences of Australian SARS-CoV-2 isolates revealed deletions and mutations in the Coronavirus 3′ stem-loop II-like motif (s2m), suggesting potential RNA recombination events.
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| August 2020 |
Deinococcus radiodurans
Scientists reported findings that Deinococcus radiodurans bacteria can survive for three years in outer space, based on studies conducted on the International Space Station, supporting the panspermia hypothesis.
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| 2019 |
DNA damage
A scientific paper identified proteins promoting endogenous DNA damage, termed DNA 'damage-up' proteins (DDPs), which were found to operate through three distinct mechanisms of cellular DNA damage.
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| 2018 |
Deinococcus radiodurans
M. Peana and C. Chasapis used bioinformatic strategies to identify and propose a model for Manganese-binding proteins in the D. radiodurans genome, exploring their role in reactive oxygen species (ROS) response and defense.
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| 2016 |
Deinococcus radiodurans
Massimiliano Peana et al. conducted a spectroscopic study using NMR, EPR, and ESI-MS techniques to examine the interaction of Mn(II) with two specific peptides (DP1 and DP2) found in Deinococcus radiodurans.
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This contents of the box above is based on material from the Wikipedia articles Homologous recombination, Deinococcus radiodurans & DNA damage (naturally occurring), which are released under the Creative Commons Attribution-ShareAlike 4.0 International License.