Gene therapy

Medical technology

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2022
Mitochondrial replacement therapy
Maeve's Law was passed by the Australian Parliament, legalising MRT under a specified mitochondrial donation licence for research, training, and clinical settings.
June 2020
Mitochondrial replacement therapy
Australian National Health and Medical Research Council issued two reports on legalising MRT.
January 2019
Mitochondrial replacement therapy
By this date, the HFEA had received 15 requests for Mitochondrial Replacement Therapy, with 14 requests granted.
January 2019
Mitochondrial replacement therapy
It was reported that seven babies had been born using MRT, with approval from an ethical committee and review board in Ukraine.
January 2019
Mitochondrial replacement therapy
Embryotools in Barcelona, Spain announced a 32-year-old Greek woman became pregnant using spindle transfer technique, performed in Greece due to MRT being illegal in Spain, with support from the Institute of Life in Athens.
2018
Mitochondrial replacement therapy
Researchers announced the use of MRT to restore function to heart tissue in cardiac-compromised newborns by extracting healthy mitochondria.
2018
Mitochondrial replacement therapy
Carl Zimmer drew a comparative analysis between the reactions to He Jiankui's human gene editing experiment and the ongoing debate over mitochondrial replacement therapy.
July 2018
Mitochondrial replacement therapy
Australian Senate endorsed MRT, with research and clinical applications overseen by federal and state government laws.
June 2018
Mitochondrial replacement therapy
Australian Senate's Community Affairs References Committee recommended moving towards legalising Mitochondrial Replacement Therapy (MRT).
June 2018
Mitochondrial replacement therapy
Valery Zukin from the Nadiya clinic in Kyiv, Ukraine, reported using pronuclear transfer MRT method to help four women give birth (three boys and a girl) and three additional women become pregnant, with 14 failed attempts previously.
October 2017
Mitochondrial replacement therapy
The British HFEA continued to authorize MRT for women with specific genetic mitochondrial mutations.
August 2017
Mitochondrial replacement therapy
The British HFEA (Human Fertilisation and Embryology Authority) authorized MRT for two women with genetic mitochondrial mutations causing myoclonic epilepsy with ragged red fibers.
August 2017
Mitochondrial replacement therapy
The FDA issued a warning letter to two clinics, including Zhang's, stating that the MRT technique should not be marketed in the United States.
August 2017
Mitochondrial replacement therapy
The HFEA began receiving requests from women to undergo Mitochondrial Replacement Therapy.
March 2017
Mitochondrial replacement therapy
HFEA granted its first license for Mitochondrial Replacement Therapy to Newcastle Fertility Centre, led by Dr Jane Stewart.
January 2017
Mitochondrial replacement therapy
A first mitochondrial replacement therapy (MRT) child, a boy, was born to a 34-year-old woman, with genetic test results reported as normal.
2016
Mitochondrial replacement therapy
Douglass Turnbull, the driving force behind mitochondrial research at Newcastle University, was awarded a knighthood.
2016
Mitochondrial replacement therapy
John Zhang and a mixed team of scientists from Mexico and New York used spindle transfer technique to help a Jordanian woman give birth to a baby boy, where the mother had Leigh disease and previously experienced four miscarriages and two children's deaths from the disease.
2016
Mitochondrial replacement therapy
UK regulatory authority published official regulations for mitochondrial donation, completing the legal framework for the procedure.
December 2016
Mitochondrial replacement therapy
The HFEA issued regulations for Mitochondrial Replacement Therapy.
November 2016
Mitochondrial replacement therapy
The HFEA Safety Committee issued its fourth report recommending procedures for authorizing Mitochondrial Replacement Therapy (MRT).
February 3 2016
Mitochondrial replacement therapy
The Institute of Medicine of the National Academies of Sciences, Engineering, and Medicine issued a report commissioned by the FDA, concluding that mitochondrial replacement techniques (MRT) are 'ethically permissible' under certain conditions.
October 29 2015
Mitochondrial replacement therapy
Parliament passed the Human Fertilisation and Embryology (Mitochondrial Donation) Regulations, making human mitochondrial donation legal in the UK.
2013
Mitochondrial replacement therapy
UK government recommended that mitochondrial donation be legalized after extensive research, scientific review, and public consultations.
July 2011
Mitochondrial replacement therapy
The independent committee's report recommended that existing legislation remain unchanged.
2010
Mitochondrial replacement therapy
Hon. Mark Butler MP appointed an independent committee to review the Prohibition of Human Cloning for Reproduction Act 2002 and the Research Involving Human Embryos Act 2002.

This contents of the box above is based on material from the Wikipedia article Mitochondrial replacement therapy, which is released under the Creative Commons Attribution-ShareAlike 4.0 International License.

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