He Jiankui
Chinese scientist
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| September 8 2023 | He Jiankui was appointed as the inaugural director of the Institute of Genetic Medicine at a private undergraduate college in Wuhan, Hubei. |
| February 21 2023 | Ming Pao newspaper reported that He Jiankui claimed his application for a Hong Kong entry permit through the Top Talent Pass Scheme had been approved. However, the Hong Kong Government later announced that the Immigration Department suspected false statements and invalidated his entry permit, initiating a criminal investigation. |
| 2022 | Release of documentary 'Make People Better' directed by Cody Sheehy, which describes He Jiankui's disappearance after creating the first designer babies and shocking the scientific community. |
| 2022 | The third genetically edited baby, named Amy, was revealed to the public. |
| November 24 2022 | He publicly stated his intention to develop gene therapies for three to five genetic diseases within two to three years, with a specific focus on Duchenne muscular dystrophy. |
| November 10 2022 | He announced the establishment of a new laboratory in Beijing focused on gene therapy for rare genetic diseases. |
| April 2022 | Released from prison. |
| April 2022 | He Jiankui is released from prison. |
| February 2022 | Chinese scientists proposed building a special facility to care for and study the three CRISPR Babies, suggesting regular genome sequencing and testing. |
| 2021 | Publication of documentary book 'CRISPR People: The Science and Ethics of Editing Humans' by Henry Greely, further exploring He Jiankui's genetic modification experiment. |
| January 21 2021 | Results of CRISPR-Cas9 clinical trials for blood disorders simultaneously published in The New England Journal of Medicine, documenting successful gene modification in individuals with sickle cell disease and β-thalassemia. |
| 2020 | Published book 'The Mutant Project: Inside the Global Race to Genetically Modify Humans' by Eben Kirksey, which narrates He Jiankui's story. |
| 2020 | University of Pennsylvania's Abramson Cancer Center conducted a CRISPR gene editing clinical trial on three individuals with advanced refractory cancer, using CAR T-cell therapy. |
| 2020 | The National People's Congress of China passes Civil Code and Criminal Law amendments prohibiting human gene editing and cloning, with potential prison sentences up to seven years for serious violations. |
| 2019 | He was listed in Time magazine's 100 most influential people, in the 'Pioneers' section, while also being referred to as a 'rogue scientist', 'China's Dr. Frankenstein', and a 'mad genius'. |
| 2019 | The World Health Organization (WHO) launched a global registry to track research on human genome editing and called for a halt to such work. |
| December 30 2019 | A Chinese district court found He Jiankui guilty of illegal medical practice, sentencing him to three years in prison and fining him 3 million yuan. |
| December 30 2019 | The Shenzhen Nanshan District People's Court finds He Jiankui guilty of illegal medical practice, sentencing him to three years in prison and a 3 million yuan fine. |
| December 30 2019 | The Shenzhen City Nanshan District People's Court sentenced He Jiankui to three years in prison and fined him 3 million RMB for unethical gene-editing experiments. His collaborators Zhang Renli and Qin Jinzhou also received prison sentences and fines. |
| December 30 2019 | Chinese court verdict confirmed the existence of 'three genetically-edited babies' in He Jiankui's controversial experiment. |
| December 30 2019 | A Chinese district court finds He Jiankui guilty of illegal medical practice and sentences him to three years in prison with a 3 million yuan fine. |
| December 3 2019 | MIT Technology Review reported on He Jiankui's scientific manuscripts after receiving them from an anonymous source. |
| November 19 2019 | First results announced for CRISPR-Cas9 clinical trials, showing successful treatment of two patients with β-thalassemia and sickle cell disease. |
| November 19 2019 | He Jiankui submitted a manuscript titled 'Birth of Twins After Genome Editing for HIV Resistance' to Nature, which was subsequently rejected. |
| August 2019 | A second genetically edited baby (later revealed as Amy) was born around this time, following He Jiankui's experimental gene-editing process. |
| August 2019 | A second pregnancy resulting from He Jiankui's gene editing experiment occurred, with the birth of a third genetically edited baby. |
| June 2019 | Denis Rebrikov announced plans to repeat He Jiankui's experiment after obtaining official approval, and was approached by a deaf couple to help repair a gene causing deafness. |
| June 2019 | Researchers Rasmus Nielsen and Wei Xinzhu published a controversial study in Nature Medicine suggesting that CCR5Δ32 mutations might shorten life expectancy (later retracted). |
| May 2019 | Chinese government begins preparing regulations on human genome editing. |
| April 2019 | Genetics experts from the Chinese Academy of Science (CAS) strongly condemned He Jiankui's gene-editing experiment as a gross violation of Chinese regulations and international scientific consensus. |
| February 2019 | Scientists reported that Lulu and Nana may have inadvertently had their brains altered due to the CCR5 deletion, which is linked to improved memory function in mice. |
| February 25 2019 | Speculation emerged about potential Chinese government funding of the CRISPR babies experiment, which was later disproven, with reports showing He raised funds independently to evade regulations. |
| January 29 2019 | Nobel laureate Craig Mello interviews He Jiankui about his gene-edited babies experiment. |
| January 21 2019 | He Jiankui is fired from his position at SUSTech, and the Guangdong Province administration begins investigating the 'gene editing baby incident'. |
| January 21 2019 | Fired from his position as associate professor of biology at the Southern University of Science and Technology (SUSTech). |
| January 21 2019 | He Jiankui is fired from his position at SUSTech, and his teaching and research work is terminated. |
| January 7 2019 | Reports suggested He could face severe consequences for his unauthorized gene-editing research. |
| 2018 | Initiated a documentary project on genetic engineering called Code of the Wild: The Nature of Us, which later documented He Jiankui's controversial CRISPR experiment. |
| December 28 2018 | He Jiankui was reported to be sequestered in a university apartment and under guard following his gene-editing controversy. |
| November 29 2018 | Chinese authorities suspend He Jiankui's research activities following his controversial presentation. |
| November 28 2018 | The National Institutes of Health (NIH) publicly condemned He Jiankui's research, criticizing the secretive nature of the project and questioning its medical necessity and ethical standards. |
| November 28 2018 | The organizing committee of the Second International Summit on Human Genome Editing issues a statement condemning He Jiankui's gene-editing experiment as irresponsible and unethical. |
| November 28 2018 | He Jiankui presents his research at the Second International Summit on Human Genome Editing in Hong Kong. |
| November 26 2018 | 122 Chinese scientists issue a public statement criticizing He Jiankui's research as unethical and damaging to China's scientific reputation. |
| November 26 2018 | The manuscript submitted by He Jiankui was published in The CRISPR Journal, shortly after news of his human gene editing experiment broke out. The journal later retracted the paper due to potential violations of bioethical norms. |
| November 26 2018 | 122 Chinese scientists issue a statement criticizing He Jiankui's research as unethical and damaging to Chinese science's global reputation. |
| November 26 2018 | Southern University of Science and Technology (SUSTech) publicly condemns He Jiankui's off-campus research and announces an independent investigation. |
| November 26 2018 | He Jiankui announces the birth of genome-edited babies in a series of five YouTube videos. |
| November 25 2018 | Jennifer Doudna receives urgent message about He Jiankui's gene-editing experiment with human embryos. |
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