Plasmodium
Genus of parasitic protists that can cause malaria
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We include updates on Malaria, Maurer's cleft, Plasmepsin, PlasmoDB, Reticulocyte binding protein homologs, Giovannolaia, Haemamoeba, Laverania, Novyella, Vinckeia, Huffia, Sauramoeba, Carinamoeba, Lacertamoeba, Ophidiella, Asiamoeba ... and more.
| October 2024 |
Malaria
WHO certified Egypt as malaria-free.
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| January 2024 |
Malaria
Cabo Verde was certified malaria-free by the WHO, bringing the total number of malaria-free countries and territories to 44.
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| 2023 |
Malaria
India successfully reduced malaria cases to two million (20 lakh) and malaria deaths to 3,500, representing a 69% and 68% decrease respectively since 2017.
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| 2023 |
Malaria
A report emerged about the bacterium Delftia tsuruhatensis naturally preventing malaria development by secreting a molecule called Harmane.
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| 2023 |
Malaria
World Health Organization confirmed that Azerbaijan, Tajikistan, and Belize have eliminated malaria.
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| June 2023 |
Malaria
WHO certified Belize as malaria-free.
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| March 2023 |
Malaria
WHO certified Azerbaijan and Tajikistan as malaria-free.
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| 2022 |
Malaria
A clinical trial demonstrated that the monoclonal antibody mAb L9LS provides protective effects against malaria by binding to and neutralizing the Plasmodium falciparum circumsporozoite protein (CSP-1), which is crucial in the disease mechanism.
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| 2022 |
Malaria
Global malaria cases reached 249 million, resulting in an estimated 608,000 deaths, with 80 percent of deaths affecting children five years old or younger.
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| December 2022 |
Malaria
BioNTECH initiated a Phase 1 study for their mRNA-based malaria vaccine BN165, testing it in adults aged 18-55 years to determine safe and tolerable dose levels.
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| 2021 |
Malaria
World Health Organization confirmed that China has eliminated malaria.
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| 2021 |
Malaria
International and national funding for malaria control and elimination reached $3.5 billion, which was only half of the estimated amount needed for comprehensive eradication efforts.
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| 2021 |
Malaria
Manufacturers delivered about 220 million ITNs to malaria-endemic countries, a decrease of 9 million compared to 2020. Percentage of children sleeping under ITNs in sub-Saharan Africa increased to over 50%.
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| 2021 |
Malaria
University of Oxford researchers reported findings from a Phase IIb trial of the R21/Matrix-M vaccine, demonstrating 77% efficacy over 12 months and becoming the first vaccine to meet WHO's Malaria Vaccine Technology Roadmap goal.
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| 2021 |
Malaria
World Health Organization's (WHO) Guideline Development Group conditionally recommended screening houses to reduce malaria transmission, with consideration of local factors such as delivery method, maintenance, house design, feasibility, resource needs, and scalability.
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| 2021 |
Malaria
A Cochrane review evaluated the use of community-administered ivermectin for malaria prevention, concluding that low-quality evidence showed no significant impact on reducing malaria transmission.
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| 2021 |
Malaria
United States Agency for International Development provided funding to In2Care BV to develop the EaveTube, a ventilation tube installed in housing walls designed to deter and kill mosquitoes using insecticide-treated netting.
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| 2021 |
Malaria
UNICEF reported that nearly every minute, a child under five died of malaria, highlighting the continued severity of the disease.
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| 2021 |
Malaria
El Salvador and China were declared malaria-free by the WHO.
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| April 25 2021 |
Malaria
WHO named 25 countries in its E-2025 initiative to eliminate malaria by 2025, ahead of World Malaria Day.
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| 2020 |
Malaria
Covid-19 pandemic disrupted malaria treatments, causing healthcare delays that led to increased malaria deaths globally due to lockdown measures and healthcare system strain.
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| 2020 |
Malaria
Further reduction of endemic malaria countries by an additional 20, bringing the total down to approximately 66 countries.
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| 2020 |
Malaria
Manufacturers delivered approximately 229 million ITNs to malaria-endemic countries.
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| December 2020 |
Malaria
A review article was published noting a correlation between malaria-endemic regions and lower COVID-19 case fatality rates.
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| 2019 |
Malaria
Research demonstrated the first proof of the critical role of amino sugar biosynthesis in the liver stage of P. berghei, revealing limited uptake of N-acetyl-glucosamine and the necessity of its synthesis for parasite development.
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| 2019 |
Malaria
Only 36% of households had sufficient ITNs for all household members. ITN coverage ranged from 31% in Angola to approximately 97% in Guinea-Bissau.
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| 2019 |
Malaria
Researchers conducted experimental analysis using knockout (KO) mutants of Plasmodium berghei to identify genes essential in the parasite's liver stage. They developed a computational model to analyze pre-erythrocytic development and liver-stage metabolism, identifying seven critical metabolic subsystems.
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| 2019 |
Malaria
Artemisinin and piperaquine resistance spread across Cambodia, Laos, Thailand, and Vietnam, with up to 80 percent of malaria parasites showing resistance in some regions.
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| 2019 |
Malaria
Argentina and Algeria were declared malaria-free by the WHO.
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| August 2019 |
Malaria
One locally acquired malaria case reported in Maryland, United States.
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| May 2019 |
Malaria
Four locally acquired malaria cases reported in the United States, along with one case in Texas.
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| 2018 |
Malaria
WHO announced Paraguay was free of malaria, following a national eradication effort that began in 1950.
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| 2017 |
Malaria
India recorded 6.4 million (64 lakh) malaria cases, before initiating significant reduction efforts.
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| 2017 |
Malaria
A bacterial strain of the genus Serratia was genetically modified to prevent malaria in mosquitos.
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| 2017 |
Malaria
Number of countries with endemic malaria reduced from 200 to 86.
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| 2016 |
Malaria
Bill Gates predicted global malaria eradication would be possible by 2040.
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| 2015 |
Malaria
Researchers conducted a study exploring the interaction between malaria and co-infection with the nematode Nippostrongylus brasiliensis in mice, discovering that the nematode infection reduces the virulence of the Plasmodium parasite.
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| 2015 |
Malaria
Malaria disease rates began increasing after a previous period of decline, signaling a potential reversal in global control efforts.
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| 2015 |
Malaria
WHO targeted a 90% reduction in malaria deaths by 2030.
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| 2015 |
Malaria
RTS,S vaccine was first approved by European regulators.
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| 2015 |
Malaria
68% of African children were using mosquito nets.
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| 2014 |
Malaria
Tajikistan reported the last indigenous malaria case, after which the WHO European Region became free of malaria.
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| 2014 |
Malaria
Malaria disease rates continued to decrease, reaching the end of a period of declining transmission.
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| 2013 |
Malaria
First detection of resistance to the combination of artemisinin and piperaquine in Cambodia, signaling a critical development in antimalarial drug resistance.
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| 2013 |
Malaria
WHO and the malaria vaccine funders group set a goal to develop vaccines designed to interrupt malaria transmission with long-term eradication in mind.
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| 2012 |
Malaria
The Malaria Policy Advisory Committee (MPAC) of the World Health Organization (WHO) was formed to provide strategic advice on malaria control and elimination.
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| 2011 |
Malaria
Percentage of children sleeping under ITNs in sub-Saharan Africa was less than 40%.
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| 2010 |
Malaria
Publication of an updated map of P. falciparum malaria endemicity, identifying the global spatial limits of the disease.
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| 2010 |
Malaria
China announced a national strategy to pursue malaria elimination in its provinces.
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This contents of the box above is based on material from the Wikipedia article Malaria, which is released under the Creative Commons Attribution-ShareAlike 4.0 International License.