Sarah Tabrizi

British neurologist and neuroscientist

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2024 Elected Fellow of the Royal Society, a prestigious scientific honor highlighting her outstanding scientific achievements.
2024 Elected to US National Academy of Medicine, recognizing her significant contributions to medical research.
2023 Received the Arvid Carlsson Award from Lund University, acknowledging her notable work in neuroscience.
2022 Awarded the MRC Millennium Medal in recognition of her significant medical research contributions.
2022 Honored with the Osler Medal and Lecture from the Association of Physicians of Great Britain and Ireland.
2022 Received the Huntington's Disease Society of America Outstanding Research Award for her groundbreaking work in Huntington's disease research.
2022 Developed the Huntington's Disease Integrated Staging System (HD-ISS) alongside colleagues, creating a novel four-stage framework for assessing disease progression from birth, similar to cancer staging systems.
2020 Published the Huntington's Disease Young Adult Study (HD-YAS), which studied premanifest HD gene carriers approximately 24 years from predicted onset of clinical symptoms, providing critical information on the earliest signs of neurodegeneration.
2020 Reviewed the potential of antisense oligonucleotides to treat neurodegenerative diseases in Science journal.
2019 Awarded the Yahr Award from the World Congress of Neurology for her contributions to neuroscience.
2019 Received the Alexander Morison Medal from the Royal College of Physicians of Edinburgh.
May 2019 Published full results of the Huntingtin-lowering antisense oligonucleotide trial in The New England Journal of Medicine.
2018 Received the Cotzias Award from the Spanish Society of Neurology.
2018 Honored with the NHS70 Women Leader award.
2017 Awarded the Seventh Leslie Gehry Brenner Prize for Innovation in Science by the Hereditary Disease Foundation.
2017 Identified an important new genetic modifier of Huntington's disease progression (MSH3, a mismatch repair protein), which opened up new research avenues into targeting DNA repair pathways as potential therapeutics.
December 2017 Announced 'top line' results from the Phase 1b/2a safety trial of the first clinical trial of a 'gene silencing' or huntingtin-lowering antisense oligonucleotide (ASO) drug in Huntington's disease patients, receiving widespread national and international media coverage.
2016 Gave a keynote presentation at the Google Zeitgeist Minds conference about her research and the prospect of gene silencing for neurodegenerative disease.
2014 Elected Fellow of the Academy of Medical Sciences.
2013 Began serving as a member of the Wellcome Trust Expert Review Group on Cellular and Molecular Neuroscience.

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