Surgical oncology
Field of treating cancer through surgery
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| 2023 |
Irreversible electroporation
Frühling et al. published a comprehensive study on 149 patients with 149 liver lesions, reporting a mean overall survival of 27.0 months for some tumor types and 35.0 months for others.
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| 2023 |
Irreversible electroporation
Irreversible electroporation (IRE) is being widely used and evaluated in humans as a cardiac ablation therapy to treat heart rhythm irregularities by precisely killing small areas of heart muscle using high-voltage electrical pulses.
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| June 2020 |
Irreversible electroporation
Review of clinical studies on irreversible electroporation (IRE) for potential treatment of pancreas, liver, prostate, and kidney conditions revealed no randomized multicenter trials or long-term follow-up studies as of this date.
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| 2019 |
Irreversible electroporation
Ruarus et al. published a clinical study on IRE for LAPC and local recurrence, involving 50 patients (40 LAPC, 10 local recurrence) with a median tumor size of 4.0 cm, using a percutaneous approach.
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| 2019 |
Irreversible electroporation
Månsson et al. conducted a study on IRE for LAPC before chemotherapy, involving 24 patients with a median tumor size of 3.0 cm, using a percutaneous approach.
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| 2018 |
Irreversible electroporation
Leen et al. conducted a study on IRE for LAPC, involving 75 patients with a median tumor size of 3.5 cm after chemotherapy, using a percutaneous approach.
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| 2018 |
Irreversible electroporation
Sugimoto et al. published a clinical study on IRE for LAPC, involving 8 patients with a median tumor size of 2.9 cm, using either open or percutaneous approaches.
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| 2018 |
Irreversible electroporation
Flak et al. published a clinical study on IRE for LAPC, involving 33 patients with a median tumor size of 3.0 cm, using predominantly percutaneous approach (32 patients) with one open surgery.
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| 2017 |
Irreversible electroporation
Vogel et al. published a clinical study on IRE for LAPC, involving 15 patients using an open surgical approach.
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| 2017 |
Irreversible electroporation
Zhang et al. conducted a study on IRE for LAPC, involving 21 patients with a median tumor size of 3.0 cm, using a percutaneous approach.
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| 2017 |
Irreversible electroporation
Belfiore et al. published a clinical study on IRE for LAPC, involving 29 patients using a percutaneous approach.
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| 2017 |
Irreversible electroporation
Frühling et al. published a clinical study on 30 patients with 38 liver lesions, showing a 65.8% efficacy at 6 months. Niessen et al. conducted another study with 71 patients and 64 liver lesions, achieving a 68.3% primary efficacy rate.
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| 2017 |
Irreversible electroporation
Scheffer et al. conducted a study on IRE for LAPC, involving 25 patients with a median tumor size of 4.0 cm, with 52% of patients having undergone prior chemotherapy, using a percutaneous approach.
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| 2016 |
Irreversible electroporation
Månsson et al. conducted a clinical study on IRE for LAPC after chemotherapy, involving 24 patients and using a percutaneous approach.
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| 2016 |
Irreversible electroporation
Kluger et al. conducted a study on IRE for LAPC, focusing on T4 stage tumors with a median size of 3.0 cm, using an open surgical approach and involving 50 patients.
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| 2016 |
Irreversible electroporation
Lambert et al. published a clinical study on IRE for LAPC, involving 21 patients with a median tumor size of 3.9 cm, using both open (19 patients) and percutaneous (2 patients) approaches.
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| 2016 |
Irreversible electroporation
Narayanan et al. published a study on IRE for LAPC, involving 50 patients with a median tumor size of 3.2 cm after chemo- or radiation therapy, using a percutaneous approach.
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| 2016 |
Irreversible electroporation
Bhutiani et al. conducted a study on 30 patients with Hepatocellular Carcinoma, achieving 97% primary efficacy. Niessen et al. also published another study with 34 patients and 59 liver lesions, demonstrating a 74.8% primary efficacy rate.
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| 2016 |
Irreversible electroporation
Yan et al. conducted a study on IRE for LAPC, involving 25 patients with a median tumor size of 4.2 cm, using an open surgical approach.
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| 2015 |
Irreversible electroporation
Martin et al. published a clinical study on Irreversible Electroporation (IRE) for Locally Advanced Pancreatic Cancer (LAPC), involving 150 patients with a median tumor size of 2.8 cm, conducted through open surgical approach.
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| 2015 |
Irreversible electroporation
Niessen et al. published a clinical study on 25 patients with 59 liver lesions, showing a 70.8% primary efficacy rate.
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| 2014 |
Irreversible electroporation
Multiple significant studies were published: Hosein et al. reported on 28 patients with 58 CRLM lesions with 97% efficacy, and Narayanan et al. conducted a study on 67 patients with 100 liver lesions.
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| 2013 |
Irreversible electroporation
Cannon et al. published a study on IRE involving 44 patients with 48 liver lesions, using various approaches including percutaneous, open, and laparoscopic methods, with a 59.5% primary efficacy rate.
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| 2012 |
Irreversible electroporation
Kingham et al. conducted a clinical study on IRE, analyzing 28 patients with 65 liver lesions, demonstrating a 93.8% primary efficacy rate.
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| 2011 |
Irreversible electroporation
Thomson et al. published a clinical study on Irreversible Electroporation (IRE) for liver tumors, examining 25 patients with 63 lesions, including Hepatocellular Carcinoma (HCC) and Colorectal Liver Metastases (CRLM).
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| 2011 |
Irreversible electroporation
IRE began being used against prostate cancer, initially through clinical trials, compassionate care, and individualized treatment approaches.
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This contents of the box above is based on material from the Wikipedia article Irreversible electroporation, which is released under the Creative Commons Attribution-ShareAlike 4.0 International License.