Testosterone
Primary male sex hormone
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February 2025 |
Testosterone
The US Food and Drug Administration (FDA) specified label changes for testosterone products, removing language about increased cardiovascular risk from the boxed warning and adding a new warning about increased blood pressure.
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2023 |
Testosterone
Results from the TRAVERSE trial were submitted, concluding no increase in risk of adverse cardiovascular outcomes for men using testosterone for hypogonadism.
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2023 |
Pattern hair loss
Researchers published a study in the journal PNAS demonstrating that increasing production of a specific microRNA in hair follicle stem cells can soften the cells and stimulate hair growth in genetically engineered mice. The study proposed using nanoparticles for potential future topical human treatment of hair loss.
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2022 |
Testosterone
Testosterone became the 118th most commonly prescribed medication in the United States, with over 5 million prescriptions issued.
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2020 |
Testosterone
The American College of Physicians issued a guideline supporting discussions about testosterone supplementation for adult men with age-related low testosterone levels experiencing sexual dysfunction. The guideline recommends yearly evaluations and suggests considering intramuscular treatments over transdermal treatments.
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November 2020 |
Testosterone regulations in women's athletics
Semenya announced her intention to file an appeal against the IAAF testosterone rule at the European Court of Human Rights.
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September 8 2020 |
Testosterone regulations in women's athletics
The Swiss Federal Supreme Court issued a final ruling denying Semenya's appeal against the testosterone regulations.
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July 2020 |
Testosterone regulations in women's athletics
Francine Niyonsaba finished 5th in the 10000m, setting a new National Record for her country.
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July 2020 |
Testosterone regulations in women's athletics
Francine Niyonsaba competed in the 5000m but was disqualified for lane infringement while running among the leaders in her heat.
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July 2020 |
Testosterone regulations in women's athletics
At the Tokyo Olympics, several African athletes were withdrawn from their original events due to eligibility regulations related to testosterone levels, including Christine Mboma, Beatrice Masilingi, Aminatou Seyni, Caster Semenya, Margaret Wambui, and Francine Niyonsaba.
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July 2020 |
Testosterone regulations in women's athletics
Christine Mboma of Namibia won a silver medal in the 200m after being displaced from her original 400m event, becoming an 18-year-old standout athlete in the controversy surrounding testosterone regulations.
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2019 |
Testosterone regulations in women's athletics
Francine Niyonsaba, the silver medalist from the 2016 Olympics, publicly confirmed having an XY-specific Disorder of Sex Development (DSD) in an interview.
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October 2019 |
Testosterone regulations in women's athletics
Semenya, along with silver medalist Francine Niyonsaba and Olympic bronze medalist Margaret Wambui, missed the World Athletics Championships in Doha due to the new regulations.
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July 2019 |
Testosterone regulations in women's athletics
Semenya publicly stated that the ongoing legal and regulatory issues have 'destroyed' her 'mentally and physically'.
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July 30 2019 |
Testosterone regulations in women's athletics
The Swiss Federal Supreme Court reversed its earlier suspension, allowing the original Court of Arbitration for Sport decision to stand.
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June 3 2019 |
Testosterone regulations in women's athletics
Semenya appealed the decision to the Swiss Federal Supreme Court, which initially instructed the IAAF to suspend the eligibility regulations for her specific case.
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May 8 2019 |
Testosterone regulations in women's athletics
New IAAF regulations on testosterone in women's athletics came into effect, specifically targeting XY individuals with differences of sex development (DSD).
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May 1 2019 |
Testosterone regulations in women's athletics
Caster Semenya lost her case at the Court of Arbitration for Sport, with proceedings revealing she has 5α-reductase deficiency and discussing her unique hormonal biology.
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2018 |
Testosterone
A meta-analysis concluded that testosterone treatment is associated with a modest reduction in depressive symptoms in men, with enhanced effectiveness at higher doses and in carefully selected patient populations.
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November 1 2018 |
Testosterone regulations in women's athletics
The new IAAF testosterone regulations were set to become effective, with stricter rules targeting athletes with specific Disorders of Sexual Development (DSDs).
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October 2018 |
EC586
Evestra planned to seek Investigational New Drug status for EC586 in the fourth quarter of the year.
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June 19 2018 |
Testosterone regulations in women's athletics
Caster Semenya announced her intention to legally challenge the IAAF's testosterone regulations, resulting in the rules being suspended pending legal resolution.
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April 23 2018 |
Testosterone regulations in women's athletics
IAAF published new testosterone regulations for women's athletics, covering events from 400m to 1 mile, requiring athletes to reduce testosterone below 5 nmol/L to compete.
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August 2016 |
Testosterone regulations in women's athletics
During the Rio 2016 Olympic Games, a controversy erupted over testosterone regulations when South African runner Caster Semenya's participation sparked criticism from competitors Lynsey Sharp and Joanna Jóźwik, who claimed she had a competitive advantage.
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2015 |
Testosterone
The FDA stated that neither the benefits nor the safety of testosterone have been established for low testosterone levels due to aging, and required pharmaceutical labels to include warning information about potential increased risks of heart attacks and stroke.
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2014 |
Testosterone
A meta-analysis revealed that testosterone improves mood, with notable effects in middle-aged hypogonadal men experiencing subthreshold depression, though showing limited impact in older or eugonadal men.
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September 2014 |
Testosterone
FDA initiated a review of the appropriateness and safety of Testosterone Replacement Therapy (TRT) due to potential adverse cardiovascular outcomes.
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January 31 2014 |
Testosterone
FDA announced an investigation into reports of strokes, heart attacks, and deaths in men taking FDA-approved testosterone-replacement therapy.
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2013 |
Testosterone
A study published in the Journal of the American Medical Association reported that testosterone therapy was significantly associated with increased risk of adverse outcomes.
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2011 |
Testosterone regulations in women's athletics
World Athletics (then IAAF) first published testosterone regulations for women athletes, initially applying to all women with high testosterone levels.
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This contents of the box above is based on material from the Wikipedia articles Testosterone poisoning, EC586, Testosterone (medication), Testosterone regulations in women's athletics & Pattern hair loss, which are released under the Creative Commons Attribution-ShareAlike 4.0 International License.