Epigenetics
Study of DNA modifications that do not change its sequence
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We include updates on Theophylline, Sex-determination system, DNA methylation, Histone, Nucleosome, Methylation, Neurobiological effects of physical exercise, Genomic imprinting, Sexual differentiation in humans, X-inactivation, Sex-determining region Y protein, Transgenerational epigenetic inheritance, Edith Heard, H3K4me3, Histone acetyltransferase, Epigenetic clock ... and more.
| March 2023 |
Genomic imprinting
Viable bipaternal embryos were created.
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| 2022 |
Behavioral epigenetics
Research reviewed molecular mechanisms of methylation creation and removal, including signal-responsive TOP2B-induced double-strand breaks in immediate early genes during memory formation.
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| 2022 |
Epigenome editing
Research explored epigenome editing applications for multiple medical conditions, including reducing tau protein levels, regulating proteins in Huntington's disease, targeting an inherited form of obesity, and addressing Dravet syndrome.
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| 2022 |
Genomic imprinting
Parthenogenesis experimentally achieved in mice.
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| 2021 |
Epigenome editing
Researchers demonstrated potential therapeutic use of epigenome editing by repressing Nav1.7 gene expression via CRISPR-dCas9 in three mouse models of chronic pain.
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| 2018 |
Genomic imprinting
Genome editing allowed for creation of bipaternal and viable bimaternal mouse embryos.
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| 2015 |
Behavioral epigenetics
Research concluded that long-term memory formation requires gene transcription activation and de novo protein synthesis, with DNA methylation and demethylation identified as a key mechanism for regulating memory-related genes.
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| 2013 | Functional genomic research published revealing DNA methylation's role in alternative splicing and gene regulation in honey bees. |
| 2010 |
Behavioral epigenetics
A review was published discussing the role of DNA methylation in memory formation and storage, highlighting the unclear mechanisms involving neuronal function, memory, and methylation reversal.
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This contents of the box above is based on material from the Wikipedia articles Epigenome editing, Behavioral epigenetics, Genomic imprinting, Methylation & Nutritional epigenetics, which are released under the Creative Commons Attribution-ShareAlike 4.0 International License.